Reactome | Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate

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Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate Show undefined attributes

catalystActivity	[CatalystActivity:9999442] 3'(2'),5'-bisphosphate nucleotidase activity of BPNT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9999444
displayName	Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
eventOf	[Pathway:R-MMU-156584] Cytosolic sulfonation of small molecules - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:80798] 3'-phosphoadenosine 5'-phosphosulfate metabolic process
inferredFrom	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-158466] PAP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-MMU-158468] SULT1A1 dimer sulfonates PARA to PARA-SO4 - Mus musculus [Reaction:R-MMU-158860] SULT1A1 dimer sulfonates NHABP - Mus musculus [Reaction:R-MMU-158849] Phenol can form a sulfate conjugate - Mus musculus [Reaction:R-MMU-159358] SULT1A3,4 dimers sulfate DA to DAOS - Mus musculus [Reaction:R-MMU-176585] 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP - Mus musculus [Reaction:R-MMU-176474] 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP - Mus musculus [Reaction:R-MMU-176646] p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP - Mus musculus [Reaction:R-MMU-176669] N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP - Mus musculus [Reaction:R-MMU-176609] cholesterol + PAPS => cholesterol sulfate + PAP - Mus musculus [Reaction:R-MMU-176494] SULTs transfer (SO4)2- group to 27HCHOL - Mus musculus [Reaction:R-MMU-176517] SULTs transfer (SO4)2- group to PREG - Mus musculus [Reaction:R-MMU-176664] estrone + PAPS => estrone 3-sulfate + PAP - Mus musculus [Reaction:R-MMU-176631] dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP - Mus musculus [Reaction:R-MMU-176521] beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP - Mus musculus [Reaction:R-MMU-176588] lithocholate + PAPS => lithocholate sulfate + PAP - Mus musculus [Reaction:R-MMU-176604] taurolithocholate + PAPS => taurolithocholate sulfate + PAP - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-176606
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-156584] Cytosolic sulfonation of small molecules
(inferredTo)	[Reaction:R-HSA-176606] Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate

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