Reactome | RFC dissociates after sliding clamp formation on the C-strand of the telomere

Schema > Reaction > Entries

RFC dissociates after sliding clamp formation on the C-strand of the telomere Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9998894
displayName	RFC dissociates after sliding clamp formation on the C-strand of the telomere
eventOf	[Pathway:R-MMU-174411] Polymerase switching on the C-strand of the telomere - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-174448] Formation of Processive Complex on the C-strand of the telomere - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:263978] telomere maintenance via semi-conservative replication
inferredFrom	[Reaction:R-HSA-174447] RFC dissociates after sliding clamp formation on the C-strand of the telomere - Homo sapiens
input	[Complex:R-MMU-174449] RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RFC dissociates after sliding clamp formation on the C-strand of the telomere
output	[CandidateSet:R-MMU-9668941] RFC,(CFT18-RFC) [nucleoplasm] [Complex:R-MMU-174450] RNA primer-DNA primer:G-strand extended telomere:PCNA [nucleoplasm]
precedingEvent	[Reaction:R-MMU-174439] Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-174447
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-174411] Polymerase switching on the C-strand of the telomere
(precedingEvent)	[Reaction:R-MMU-174448] Formation of Processive Complex on the C-strand of the telomere
(inferredTo)	[Reaction:R-HSA-174447] RFC dissociates after sliding clamp formation on the C-strand of the telomere

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