Reactome | APC/C:Cdc20 mediated degradation of Cyclin B

Schema > Pathway > Entries

APC/C:Cdc20 mediated degradation of Cyclin B Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099435
displayName	APC/C:Cdc20 mediated degradation of Cyclin B
eventOf	[Pathway:R-MMU-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-174120] Association of Cyclin B:Cdc2 with Cdc20:APC/C complex - Mus musculus [Reaction:R-MMU-174227] Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex - Mus musculus [BlackBoxEvent:R-MMU-174157] Degradation of multiubiquitinated Cyclin B - Mus musculus
inferredFrom	[Pathway:R-HSA-174048] APC/C:Cdc20 mediated degradation of Cyclin B - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	APC/C:Cdc20 mediated degradation of Cyclin B
precedingEvent	[Pathway:R-MMU-174184] Cdc20:Phospho-APC/C mediated degradation of Cyclin A - Mus musculus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-174048
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-176409] APC/C:Cdc20 mediated degradation of mitotic proteins
(inferredTo)	[Pathway:R-HSA-174048] APC/C:Cdc20 mediated degradation of Cyclin B

Cite Us!