Reactome | Crk's SH3 domain engages C3G

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Crk's SH3 domain engages C3G Show undefined attributes

category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9997124
displayName	Crk's SH3 domain engages C3G
eventOf	[Pathway:R-MMU-170984] ARMS-mediated activation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-169904] C3G stimulates nucleotide exchange on Rap1 - Mus musculus
inferredFrom	[Reaction:R-HSA-169895] Crk's SH3 domain engages C3G - Homo sapiens
input	[Complex:R-MMU-169865] Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Crk's SH3 domain engages C3G
output	[Complex:R-MMU-169865] Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane]
precedingEvent	[Reaction:R-MMU-169905] ARMS is phosphorylated by active TrkA receptor - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-169895
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-170984] ARMS-mediated activation
(precedingEvent)	[Reaction:R-MMU-169904] C3G stimulates nucleotide exchange on Rap1
(inferredTo)	[Reaction:R-HSA-169895] Crk's SH3 domain engages C3G

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