Reactome | Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans

Schema > Reaction > Entries

Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans Show undefined attributes

catalystActivity	[CatalystActivity:10036168] protein sequestering activity of HPSE2(1-592) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10036170
displayName	Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans
eventOf	[Pathway:R-MMU-2024096] HS-GAG degradation - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1678694] Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-1678680] Hpse2 [plasma membrane] [DefinedSet:R-MMU-2076639] HS/HPIN-PGs [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans
output	[Complex:R-MMU-9774311] HPSE2:HS/HPIN-PGs [plasma membrane]
precedingEvent	[BlackBoxEvent:R-MMU-2024108] Some HSPGs are secreted to the plasma membrane - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1678694
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-2024096] HS-GAG degradation
(inferredTo)	[Reaction:R-HSA-1678694] Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans

Cite Us!