Reactome | G protein alpha:GTP complex [plasma membrane]

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G protein alpha:GTP complex [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:10014454] GTPase activity of G-protein alpha (q/11): GTP [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-8982027] G alpha (q):GTP:RGS [plasma membrane] - Mus musculus [Complex:R-MMU-8964296] Active Gq:BTK [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-418582] G alpha (q) auto-inactivates by hydrolysing GTP to GDP - Mus musculus [Reaction:R-MMU-416516] GRK2 sequesters activated Gq - Mus musculus [Reaction:R-MMU-8982017] Active G alpha (q) binds RGS proteins - Mus musculus [Reaction:R-MMU-416358] G alpha (q) inhibits PI3K alpha - Mus musculus [Reaction:R-MMU-8964280] Active Gq binds BTK - Mus musculus [Reaction:R-MMU-400586] G alpha (q) binds to Trio family RhoGEFs - Mus musculus [Reaction:R-MMU-167415] G-protein alpha subunit is inactivated - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9992229
displayName	G protein alpha:GTP complex [plasma membrane]
hasComponent	[DefinedSet:R-MMU-167413] G-protein alpha (q/11/14/15) [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-114534] G-protein alpha (q/11): GTP [plasma membrane] - Homo sapiens [Complex:R-HSA-167438] G protein alpha:GTP complex [plasma membrane] - Homo sapiens
maxDepth	3
name	G protein alpha:GTP complex
producedByEvent	[Reaction:R-MMU-397835] Thrombin-activated PARs:Gq (active) dissociate - Mus musculus [Reaction:R-MMU-749452] The Ligand:GPCR:Gq complex dissociates - Mus musculus [Reaction:R-MMU-8964340] Gq-BTK complex dissociates to Active BTK and Gq - Mus musculus [Reaction:R-MMU-112271] The receptor:G-protein complex dissociates - Mus musculus [Reaction:R-MMU-428752] Dissociation of the TP:Gq complex - Mus musculus [Reaction:R-MMU-418576] Dissociation of the P2Y purinoceptor 1:Gq complex - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-167438
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-MMU-8964340] Gq-BTK complex dissociates to Active BTK and Gq [Reaction:R-MMU-428752] Dissociation of the TP:Gq complex [Reaction:R-MMU-112271] The receptor:G-protein complex dissociates [Reaction:R-MMU-397835] Thrombin-activated PARs:Gq (active) dissociate [Reaction:R-MMU-749452] The Ligand:GPCR:Gq complex dissociates [Reaction:R-MMU-418576] Dissociation of the P2Y purinoceptor 1:Gq complex
(input)	[Reaction:R-MMU-8964280] Active Gq binds BTK [Reaction:R-MMU-418582] G alpha (q) auto-inactivates by hydrolysing GTP to GDP [Reaction:R-MMU-400586] G alpha (q) binds to Trio family RhoGEFs [Reaction:R-MMU-416516] GRK2 sequesters activated Gq [Reaction:R-MMU-8982017] Active G alpha (q) binds RGS proteins [Reaction:R-MMU-416358] G alpha (q) inhibits PI3K alpha [Reaction:R-MMU-167415] G-protein alpha subunit is inactivated
(hasComponent)	[Complex:R-MMU-8964296] Active Gq:BTK [plasma membrane] [Complex:R-MMU-400608] G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] [Complex:R-MMU-416515] G-protein alpha (q):GRK2 [plasma membrane] [Complex:R-MMU-8982027] G alpha (q):GTP:RGS [plasma membrane] [Complex:R-MMU-416356] G-protein alpha (q/11):PI3K alpha [plasma membrane] [Complex:R-MMU-167439] G protein-GTP [plasma membrane] [Complex:R-MMU-111856] Activated PLC beta 1/4 [plasma membrane]
(physicalEntity)	[CatalystActivity:10014454] GTPase activity of G-protein alpha (q/11): GTP [plasma membrane]
(inferredTo)	[Complex:R-HSA-114534] G-protein alpha (q/11): GTP [plasma membrane] [Complex:R-HSA-167438] G protein alpha:GTP complex [plasma membrane]

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