Reactome | RHEB:GTP [lysosomal membrane]

Schema > Complex > Entries

compartment	[Compartment:17938] lysosomal membrane
componentOf	[Complex:R-MMU-9646467] v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] - Mus musculus [Complex:R-MMU-9646465] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-165680] Formation of active mTORC1 complex - Mus musculus [Reaction:R-MMU-9646468] mTORC1 binds RHEB:GTP - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9996240
displayName	RHEB:GTP [lysosomal membrane]
hasComponent	[SimpleEntity:R-ALL-29438] GTP [cytosol] [EntityWithAccessionedSequence:R-MMU-165190] RHEB [lysosomal membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-165189] RHEB:GTP [lysosomal membrane] - Homo sapiens
maxDepth	2
name	RHEB:GTP
producedByEvent	[Reaction:R-MMU-165195] GTP loading by Rheb - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-165189
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9646468] mTORC1 binds RHEB:GTP [Reaction:R-MMU-165680] Formation of active mTORC1 complex
(hasComponent)	[Complex:R-MMU-9646465] v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] [Complex:R-MMU-9646467] v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] [Complex:R-MMU-165678] Active mTORC1 complex [lysosomal membrane] [Complex:R-MMU-5693284] mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
(output)	[Reaction:R-MMU-165195] GTP loading by Rheb
(inferredTo)	[Complex:R-HSA-165189] RHEB:GTP [lysosomal membrane]