Reactome | CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine

Schema > Reaction > Entries

CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine Show undefined attributes

catalystActivity	[CatalystActivity:10035376] cysteine dioxygenase activity of CDO1:Fe2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10035378
displayName	CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine
eventOf	[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:10761] L-cysteine catabolic process
inferredFrom	[Reaction:R-HSA-1614645] CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine - Homo sapiens
input	[SimpleEntity:R-ALL-111707] L-Cys [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine L-cysteine + O2 => 3-sulfino-L-alanine + H(+)
output	[SimpleEntity:R-ALL-1614519] 3-Sulfinoalanine [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-MMU-1614583] PXLP-K212-CTH cleaves L-Cystathionine - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1614645
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1614558] Degradation of cysteine and homocysteine
(inferredTo)	[Reaction:R-HSA-1614645] CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine

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