Reactome | gamma-secretase complex [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10005921] peptidase activity of gamma-secretase complex [plasma membrane] [CatalystActivity:10001709] endopeptidase activity of gamma-secretase complex [plasma membrane] [CatalystActivity:10086158] aspartic-type endopeptidase activity of gamma-secretase complex [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10001708
displayName	gamma-secretase complex [plasma membrane]
hasComponent	[DefinedSet:R-MMU-157341] APH-1 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-2534241] Ncstn [plasma membrane] [DefinedSet:R-MMU-9013333] Presenilin [plasma membrane] [EntityWithAccessionedSequence:R-MMU-157331] Psenen [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-157343] gamma-secretase complex [plasma membrane] - Homo sapiens
maxDepth	4
name	gamma-secretase complex
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-157343
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10005921] peptidase activity of gamma-secretase complex [plasma membrane] [CatalystActivity:10001709] endopeptidase activity of gamma-secretase complex [plasma membrane] [CatalystActivity:10086158] aspartic-type endopeptidase activity of gamma-secretase complex [plasma membrane]
(inferredTo)	[Complex:R-HSA-157343] gamma-secretase complex [plasma membrane]