Reactome | Polo-like kinase mediated events

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Polo-like kinase mediated events Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10099127
displayName	Polo-like kinase mediated events
eventOf	[Pathway:R-MMU-69275] G2/M Transition - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:171508] regulation of cell cycle
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-156699] Inactivation of Wee1 kinase - Mus musculus [Reaction:R-MMU-156678] Activation of Cdc25C - Mus musculus [Reaction:R-MMU-162657] Inactivation of Myt1 kinase - Mus musculus [Reaction:R-MMU-4088130] PLK1 binds FOXM1 - Mus musculus [Reaction:R-MMU-4088134] PLK1 phosphorylates FOXM1 - Mus musculus
inferredFrom	[Pathway:R-HSA-156711] Polo-like kinase mediated events - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Polo-like kinase mediated events
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-156711
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-69275] G2/M Transition
(inferredTo)	[Pathway:R-HSA-156711] Polo-like kinase mediated events

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