Reactome | Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)

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Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) Show undefined attributes

catalystActivity	[CatalystActivity:10033755] ferroxidase activity of Ferritin Complex [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10033757
displayName	Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)
eventOf	[Pathway:R-MMU-917937] Iron uptake and transport - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1562626] Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) - Homo sapiens
input	4 × [SimpleEntity:R-ALL-71067] Fe2+ [cytosol] 4 × [SimpleEntity:R-ALL-70106] H+ [cytosol] 4 × [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)
output	4 × [SimpleEntity:R-ALL-5691103] Fe(3+)O(OH) [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1562626
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-917937] Iron uptake and transport
(inferredTo)	[Reaction:R-HSA-1562626] Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)

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