Reactome | TRAF2:TRADD:RIPK1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-140977] TRADD:TRAF2:RIPK1:FADD [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9819106] ULK1 phosphorylates RIPK1 at S357 - Mus musculus [Reaction:R-MMU-140978] TRADD:TRAF2:RIP1 binds FADD - Mus musculus [Reaction:R-MMU-9815501] MAPKAPK2 phosphorylates RIPK1 at S320 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9990992
displayName	TRAF2:TRADD:RIPK1 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-MMU-168651] RIPK1 [cytosol] 3 × [EntityWithAccessionedSequence:R-MMU-66376] TRADD [cytosol] 3 × [EntityWithAccessionedSequence:R-MMU-66370] Traf2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-140935] TRAF2:TRADD:RIPK1 [cytosol] - Homo sapiens
maxDepth	2
name	TRAF2:TRADD:RIPK1
producedByEvent	[Reaction:R-MMU-83582] TRADD:TRAF2:RIP1 dissociates from TNF-?:TNFR1 - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-140935
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9819106] ULK1 phosphorylates RIPK1 at S357 [Reaction:R-MMU-9815501] MAPKAPK2 phosphorylates RIPK1 at S320 [Reaction:R-MMU-140978] TRADD:TRAF2:RIP1 binds FADD
(output)	[Reaction:R-MMU-83582] TRADD:TRAF2:RIP1 dissociates from TNF-?:TNFR1
(hasComponent)	[Complex:R-MMU-140977] TRADD:TRAF2:RIPK1:FADD [cytosol]
(inferredTo)	[Complex:R-HSA-140935] TRAF2:TRADD:RIPK1 [cytosol]