Reactome | FVa:FXa [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:9993567] serine-type endopeptidase activity of FVa:FXa [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-9932972] SERPINA10:FXa:FVa [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9015122] Factor Xa inhibitors bind Va:Xa - Mus musculus [BlackBoxEvent:R-MMU-9932951] SERPINA10:PROZ binds FXa - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9993566
displayName	FVa:FXa [plasma membrane]
hasComponent	[Complex:R-MMU-140661] factor Va [plasma membrane] [Complex:R-MMU-140649] factor Xa [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-140662] FVa:FXa [plasma membrane] - Homo sapiens
maxDepth	3
name	FVa:FXa
producedByEvent	[Reaction:R-MMU-140686] factor Va + factor Xa -> Va:Xa complex (prothrombinase) - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-140662
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9015122] Factor Xa inhibitors bind Va:Xa [BlackBoxEvent:R-MMU-9932951] SERPINA10:PROZ binds FXa
(hasComponent)	[Complex:R-MMU-9932972] SERPINA10:FXa:FVa [plasma membrane] [Complex:R-MMU-9015116] Va:Xa:Factor Xa inhibitors [plasma membrane]
(output)	[Reaction:R-MMU-140686] factor Va + factor Xa -> Va:Xa complex (prothrombinase)
(physicalEntity)	[CatalystActivity:9993567] serine-type endopeptidase activity of FVa:FXa [plasma membrane]
(inferredTo)	[Complex:R-HSA-140662] FVa:FXa [plasma membrane]