Reactome | p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10030463
displayName	p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2
eventOf	[Pathway:R-MMU-1538133] G0 and Early G1 - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 - Homo sapiens
input	[Complex:R-MMU-187496] Cyclin E/A:CDK2 [nucleoplasm] [Complex:R-MMU-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2
output	[Complex:R-MMU-1363300] RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1363303
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-1538133] G0 and Early G1
(inferredTo)	[Reaction:R-HSA-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2

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