Reactome | 2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10030430] cysteine desulfurase activity of 2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix]
compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[BlackBoxEvent:R-MMU-1362408] FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10030427
displayName	2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix]
hasComponent	2 × [Complex:R-MMU-1362402] 2 Iron:FXN [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-MMU-1362391] ISCU-1 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-MMU-1362392] LYRM4 [mitochondrial matrix] 2 × [EntityWithAccessionedSequence:R-MMU-1362396] PXLP-K258-NFS1-1 [mitochondrial matrix]
inDisease	false
inferredFrom	[Complex:R-HSA-1362401] 2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix] - Homo sapiens
maxDepth	3
name	2 Iron:FXN:NFS1:ISD11:ISCU
producedByEvent	[Reaction:R-MMU-1362416] Frataxin binds iron - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-1362401
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-MMU-1362408] FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster
(physicalEntity)	[CatalystActivity:10030430] cysteine desulfurase activity of 2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix]
(output)	[Reaction:R-MMU-1362416] Frataxin binds iron
(inferredTo)	[Complex:R-HSA-1362401] 2 Iron:FXN:NFS1:ISD11:ISCU [mitochondrial matrix]

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