Reactome | Acrosome Reaction and Sperm:Oocyte Membrane Binding

Schema > Pathway > Entries

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100665
displayName	Acrosome Reaction and Sperm:Oocyte Membrane Binding
eventOf	[Pathway:R-MMU-1187000] Fertilization - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21319] acrosome reaction
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-1297354] Acrosin Cleavage - Mus musculus [Reaction:R-MMU-1297333] Association of Acrosin Heavy and Light Chain - Mus musculus [Reaction:R-MMU-1297275] CD9:Izumo Binding - Mus musculus
inferredFrom	[Pathway:R-HSA-1300645] Acrosome Reaction and Sperm:Oocyte Membrane Binding - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Acrosome Reaction and Sperm:Oocyte Membrane Binding
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-1300645
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-1187000] Fertilization
(inferredTo)	[Pathway:R-HSA-1300645] Acrosome Reaction and Sperm:Oocyte Membrane Binding

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