Reactome | Tandem pore domain halothane-inhibited K+ channel (THIK)

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Tandem pore domain halothane-inhibited K+ channel (THIK) Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100673
displayName	Tandem pore domain halothane-inhibited K+ channel (THIK)
eventOf	[Pathway:R-MMU-1296346] Tandem pore domain potassium channels - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1042694] potassium ion transmembrane transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-1299297] Activation of THIK - Mus musculus
inferredFrom	[Pathway:R-HSA-1299287] Tandem pore domain halothane-inhibited K+ channel (THIK) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Tandem pore domain halothane-inhibited K+ channel (THIK)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-1299287
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1296346] Tandem pore domain potassium channels
(inferredTo)	[Pathway:R-HSA-1299287] Tandem pore domain halothane-inhibited K+ channel (THIK)

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