Reactome | HCN channels

Schema > Pathway > Entries

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100651
displayName	HCN channels
eventOf	[Pathway:R-MMU-1296071] Potassium Channels - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1042694] potassium ion transmembrane transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-1297444] Binding of cAMP to HCN channels - Mus musculus [Reaction:R-MMU-1296043] Activation of HCN channels - Mus musculus [Reaction:R-MMU-9726875] HCNs:cAMP bind SNIs - Mus musculus
inferredFrom	[Pathway:R-HSA-1296061] HCN channels - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HCN channels
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-1296061
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-1296071] Potassium Channels
(inferredTo)	[Pathway:R-HSA-1296061] HCN channels