Reactome | Cleavage of ethenocytosine by TDG glycosylase

Schema > Reaction > Entries

Cleavage of ethenocytosine by TDG glycosylase Show undefined attributes

catalystActivity	[CatalystActivity:9991887] DNA N-glycosylase activity of TDG:EtCYT-dsDNA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9991889
displayName	Cleavage of ethenocytosine by TDG glycosylase
eventOf	[Pathway:R-MMU-110329] Cleavage of the damaged pyrimidine - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-110350] Displacement of TDG glycosylase by APEX1 at the AP site - Mus musculus
inferredFrom	[Reaction:R-HSA-110234] Cleavage of ethenocytosine by TDG glycosylase - Homo sapiens
input	[Complex:R-MMU-110190] TDG:EtCYT-dsDNA [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Cleavage of ethenocytosine by TDG glycosylase
output	[SimpleEntity:R-ALL-110233] EtCYT [nucleoplasm] [Complex:R-MMU-110191] TDG:AP-dsDNA [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-110234
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-MMU-110350] Displacement of TDG glycosylase by APEX1 at the AP site
(hasEvent)	[Pathway:R-MMU-110329] Cleavage of the damaged pyrimidine
(inferredTo)	[Reaction:R-HSA-110234] Cleavage of ethenocytosine by TDG glycosylase

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