Reactome | VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala [cytosol]

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VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:9949623] ATP hydrolysis activity of VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9949632] VCP hexamer extracts K48 polyubiquitinated alanine-tailed nascent peptide from VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide - Homo sapiens
created	[InstanceEdit:9948423] May, Bruce, 2025-05-20
dbId	9948426
displayName	VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala [cytosol]
hasComponent	[Complex:R-HSA-72499] 60S ribosomal complex [cytosol] [Complex:R-HSA-9948421] K48polyUb-nascent peptide-Alanine [cytosol] [EntityWithAccessionedSequence:R-HSA-5688967] LTN1 [cytosol] [EntityWithAccessionedSequence:R-HSA-9948358] NEMF [cytosol] [EntityWithAccessionedSequence:R-HSA-9755492] NPLOC4 [cytosol] [EntityWithAccessionedSequence:R-HSA-9948400] TCF25 [cytosol] [EntityWithAccessionedSequence:R-HSA-9668519] UFD1 [cytosol] [Complex:R-HSA-5362364] VCP hexamer [cytosol]
inDisease	false
isChimeric	false
maxDepth	5
modified	[InstanceEdit:9954763] May, Bruce, 2025-06-08
name	VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala
producedByEvent	[Reaction:R-HSA-9948427] ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9948426

Referrals

(output)	[Reaction:R-HSA-9948427] ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide
(input)	[Reaction:R-HSA-9949632] VCP hexamer extracts K48 polyubiquitinated alanine-tailed nascent peptide from VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide
(physicalEntity)	[CatalystActivity:9949623] ATP hydrolysis activity of VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide-Ala [cytosol]

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