Reactome | TCF19:NuRD represses FBP1 gene expression

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TCF19:NuRD represses FBP1 gene expression Show undefined attributes

authored	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9944720] Rothfels, Karen, 2025-04-07
dbId	9944719
displayName	TCF19:NuRD represses FBP1 gene expression
edited	[InstanceEdit:9937860] Rothfels, Karen, 2025-02-07
eventOf	[Pathway:R-HSA-9940951] Interaction of NuRD complexes with transcription factors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9944687] FBP1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9944657] Gluconeogenesis Flux in Metabolic Disease [LiteratureReference:9944665] Regulation of gene expression by glycolytic and gluconeogenic enzymes [LiteratureReference:9944666] TCF19 Promotes Cell Proliferation through Binding to the Histone H3K4me3 Mark [LiteratureReference:9944676] Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex
maxDepth	1
modified	[InstanceEdit:9974212] Rothfels, Karen, 2025-11-20
name	TCF19:NuRD represses FBP1 gene expression
output	[EntityWithAccessionedSequence:R-HSA-70476] FBP1 [cytosol]
precedingEvent	[Reaction:R-HSA-9944706] NuRD binds TCF19 at FBP1 gene - Homo sapiens
regulatedBy	[NegativeGeneExpressionRegulation:9944718] Negative gene expression regulation by 'TCF19:NuRD:FBP1 gene:H3K4 nucleosome [nucleoplasm]'
regulationReference	[RegulationReference:9944721] Negative gene expression regulation by 'TCF19:NuRD:FBP1 gene:H3K4 nucleosome [nucleoplasm]' Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9944719
summation	[Summation:9944696] FBP1 encodes fructose-1,6-bisphosphatase 1, a rate-limiting ...

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(hasEvent)

[Pathway:R-HSA-9940951] Interaction of NuRD complexes with transcription factors

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