Reactome | CCNA:CDK1 phosphorylates FZR1

Schema > Reaction > Entries

CCNA:CDK1 phosphorylates FZR1 Show undefined attributes

authored	[InstanceEdit:9929715] Orlic-Milacic, Marija, 2024-11-27
catalystActivity	[CatalystActivity:9929667] cyclin-dependent protein serine/threonine kinase activity of p-S-CCNA:p-T161-CDK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9929715] Orlic-Milacic, Marija, 2024-11-27
dbId	9929717
deleted	[Deleted:9953045] Deletion of instance: 69756 [Deleted:9953047] Deletion of instance: 69754
displayName	CCNA:CDK1 phosphorylates FZR1
edited	[InstanceEdit:9932253] Orlic-Milacic, Marija, 2024-12-18
eventOf	[Pathway:R-HSA-69273] Cyclin A/B1/B2 associated events during G2/M transition - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-174099] FZR1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9929507] Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machinery [LiteratureReference:9929665] Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability [LiteratureReference:187958] Dual regulation of the anaphase promoting complex in human cells by cyclin A-Cdk2 and cyclin A-Cdk1 complexes
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	CCNA:CDK1 phosphorylates FZR1
orthologousEvent	[Reaction:R-CEL-9929717] CCNA:CDK1 phosphorylates FZR1 - Caenorhabditis elegans [Reaction:R-DME-9929717] CCNA:CDK1 phosphorylates FZR1 - Drosophila melanogaster [Reaction:R-GGA-9929717] CCNA:CDK1 phosphorylates FZR1 - Gallus gallus [Reaction:R-XTR-9929717] CCNA:CDK1 phosphorylates FZR1 - Xenopus tropicalis [Reaction:R-DRE-9929717] CCNA:CDK1 phosphorylates FZR1 - Danio rerio [Reaction:R-SSC-9929717] CCNA:CDK1 phosphorylates FZR1 - Sus scrofa [Reaction:R-BTA-9929717] CCNA:CDK1 phosphorylates FZR1 - Bos taurus [Reaction:R-CFA-9929717] CCNA:CDK1 phosphorylates FZR1 - Canis familiaris [Reaction:R-RNO-9929717] CCNA:CDK1 phosphorylates FZR1 - Rattus norvegicus [Reaction:R-MMU-9929717] CCNA:CDK1 phosphorylates FZR1 - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [EntityWithAccessionedSequence:R-HSA-9929805] p-S151-FZR1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9929514] CDK1 phosphorylates CCNA - Homo sapiens
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9936318] Alwakeel, Alan, 2025-01-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9929717
summation	[Summation:9929799] FZR1 (also known as CDH1 or Fizzy-related protein homolog...

Referrals

(replacementInstances)	[Deleted:9953045] Deletion of instance: 69756 [Deleted:9953047] Deletion of instance: 69754
(hasEvent)	[Pathway:R-HSA-69273] Cyclin A/B1/B2 associated events during G2/M transition