Reactome | MITF-M binds the MCM5 gene

Schema > Reaction > Entries

authored	[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9926473] Rothfels, Karen, 2024-11-01
dbId	9926493
displayName	MITF-M binds the MCM5 gene
edited	[InstanceEdit:9927257] Rothfels, Karen, 2024-11-05
eventOf	[Pathway:R-HSA-9825895] Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9926532] MITF-M-dependent MCM5 gene expression - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9926323] MCM5 gene [nucleoplasm] [Complex:R-HSA-9825710] MITF-M dimer [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
maxDepth	1
modified	[InstanceEdit:9927680] Rothfels, Karen, 2024-11-08
name	MITF-M binds the MCM5 gene
output	[Complex:R-HSA-9926388] MITF-M dimer:MCM5 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-9857375] MITF dimerizes - Homo sapiens
releaseDate	2024-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9926493
summation	[Summation:9926307] MITF-M binds an E-box element at-23kb of the MCM5 promoter t...

(hasEvent)	[Pathway:R-HSA-9825895] Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence
(precedingEvent)	[BlackBoxEvent:R-HSA-9926532] MITF-M-dependent MCM5 gene expression

Cite Us!