Reactome | Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell

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Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell Show undefined attributes

authored	[InstanceEdit:9925562] Orlic-Milacic, Marija, 2024-10-17
category	transition
created	[InstanceEdit:9910611] Orlic-Milacic, Marija, 2024-05-15
dbId	9910607
displayName	Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell
edited	[InstanceEdit:9939321] Orlic-Milacic, Marija, 2025-02-25
eventOf	[CellLineagePath:R-HSA-9925563] Developmental Lineage of Pancreatic Ductal Cells - Homo sapiens
followingEvent	[CellDevelopmentStep:R-HSA-9853402] Trunk bipotent pancreatic progenitor cell produces pancreatic ductal cell - Homo sapiens
input	[Cell:R-HSA-9909323] primary multipotent pancreatic progenitor cell
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9909322] Development of the human pancreas from foregut to endocrine commitment [LiteratureReference:9922207] Mechanosignalling via integrins directs fate decisions of pancreatic progenitors [LiteratureReference:9913771] Single-cell transcriptomic and spatial landscapes of the developing human pancreas [LiteratureReference:9927555] Deciphering early human pancreas development at the single-cell level
maxDepth	1
modified	[InstanceEdit:9939322] Orlic-Milacic, Marija, 2025-02-25
name	Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell
output	[Cell:R-HSA-9910609] pancreatic trunk bipotent progenitor cell
precedingEvent	[CellDevelopmentStep:R-HSA-9909305] Duodeno-pancreatic endoderm cell produces primary multipotent pancreatic progenitor cell - Homo sapiens [CellDevelopmentStep:R-HSA-9911215] Ventral foregut endoderm cell produces primary multipotent pancreatic progenitor cell - Homo sapiens
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveRegulation:9937553] Positive regulation by '(FN1 dimer, VTN) [extracellular region]' [NegativeRegulation:9938707] Negative regulation by '(Laminin, Collagen) [extracellular region]'
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9939319] Li, Nancy T, 2025-02-21
schemaClass	CellDevelopmentStep
species	[Species:48887] Homo sapiens
stId	R-HSA-9910607
summation	[Summation:9922189] The primary multipotent pancreatic progenitor cells (MPCs...

Referrals

(precedingEvent)	[CellDevelopmentStep:R-HSA-9853402] Trunk bipotent pancreatic progenitor cell produces pancreatic ductal cell
(hasEvent)	[CellLineagePath:R-HSA-9925563] Developmental Lineage of Pancreatic Ductal Cells

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