Reactome | PSMD10 and PAAF1 bind PSMC4:PSMC5

Schema > Reaction > Entries

PSMD10 and PAAF1 bind PSMC4:PSMC5 Show undefined attributes

authored	[InstanceEdit:9908729] Orlic-Milacic, Marija, 2024-04-22
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9907977] Orlic-Milacic, Marija, 2024-04-18
dbId	9907979
displayName	PSMD10 and PAAF1 bind PSMC4:PSMC5
edited	[InstanceEdit:9917567] Orlic-Milacic, Marija, 2024-08-07
eventOf	[Pathway:R-HSA-9907900] Proteasome assembly - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9907980] Formation of the 19S regulatory particle base precursor - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9907973] PAAF1 [cytosol] [Complex:R-HSA-9907949] PSMC4:PSMC5 [cytosol] [EntityWithAccessionedSequence:R-HSA-68788] PSMD10 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9908486] Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones [LiteratureReference:9908501] Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases [LiteratureReference:9908490] Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	PSMD10 and PAAF1 bind PSMC4:PSMC5
negativePrecedingEvent	[NegativePrecedingEvent:9909129] Futile Cycle: Formation of the 26S proteasome [NegativePrecedingEvent:9909133] Futile Cycle: Formation of the spermatoproteasome
orthologousEvent	[Reaction:R-DDI-9907979] PSMD10 and PAAF1 bind PSMC4:PSMC5 - Dictyostelium discoideum [Reaction:R-CEL-9907979] PSMD10 and PAAF1 bind PSMC4:PSMC5 - Caenorhabditis elegans
output	[Complex:R-HSA-9907971] PSMD10:PSMC4:PSMC5:PAAF1 [cytosol]
precedingEvent	[Reaction:R-HSA-9907951] PSMC4 binds PSMC5 - Homo sapiens
releaseDate	2024-09-11
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9907979
summation	[Summation:9907974] During the assembly of the proteasome 19S regulatory particl...

Referrals

(hasEvent)	[Pathway:R-HSA-9907900] Proteasome assembly
(precedingEvent)	[BlackBoxEvent:R-HSA-9907980] Formation of the 19S regulatory particle base precursor

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