Reactome | Kinesins bind microtubules

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Kinesins bind microtubules Show undefined attributes

authored	[InstanceEdit:983205] Akkerman, JW, 2010-10-29
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:983242] Jupe, S, 2010-10-29
dbId	983266
displayName	Kinesins bind microtubules
edited	[InstanceEdit:1014330] Jupe, S, 2010-11-15
eventOf	[Pathway:R-HSA-983189] Kinesins - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-983259] Kinesins move along microtubules consuming ATP - Homo sapiens
input	[CandidateSet:R-HSA-8849364] Kinesins [cytosol] [Complex:R-HSA-190599] Microtubule [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:983241] Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells [LiteratureReference:983203] Isolation of a 45-kDa fragment from the kinesin heavy chain with enhanced ATPase and microtubule-binding activities [LiteratureReference:983185] A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses [LiteratureReference:984588] Kinesin-2 is a motor for late endosomes and lysosomes [LiteratureReference:984682] A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally [LiteratureReference:984716] Human chromokinesin KIF4A functions in chromosome condensation and segregation [LiteratureReference:990506] Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	Kinesins bind microtubules
orthologousEvent	[Reaction:R-XTR-983266] Kinesins bind microtubules - Xenopus tropicalis [Reaction:R-SSC-983266] Kinesins bind microtubules - Sus scrofa [Reaction:R-CFA-983266] Kinesins bind microtubules - Canis familiaris [Reaction:R-RNO-983266] Kinesins bind microtubules - Rattus norvegicus [Reaction:R-MMU-983266] Kinesins bind microtubules - Mus musculus
output	[Complex:R-HSA-983245] Kinesins:microtubule [cytosol]
precedingEvent	[Reaction:R-HSA-983194] Kinesin-1 is a heterotetramer - Homo sapiens [Reaction:R-HSA-984708] Kinesin-2 is a heterotrimer - Homo sapiens [Reaction:R-HSA-984733] Kinesin-3 is a dimer - Homo sapiens [Reaction:R-HSA-990478] Kinesin-14 is a dimer - Homo sapiens [Reaction:R-HSA-990489] Kinesin-13 is a dimer - Homo sapiens [Reaction:R-HSA-984821] Kinesin-12 is a dimer - Homo sapiens [Reaction:R-HSA-984606] Kinesin-5 is a homotetramer - Homo sapiens [Reaction:R-HSA-984609] Kinesin-8 is a dimer - Homo sapiens [Reaction:R-HSA-984648] Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin - Homo sapiens [Reaction:R-HSA-984775] Kinesin-9 is a dimer - Homo sapiens [Reaction:R-HSA-984689] Kinesin-7 is a dimer - Homo sapiens [Reaction:R-HSA-984671] Chromokinesins form dimers - Homo sapiens
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1013883] Ouwehand, WH, 2010-11-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-983266
summation	[Summation:990477] All kinesins contain a motor domain or head, the position va...
updateTrackers	[UpdateTracker:9783584] Update Tracker - [Reaction:983266] Kinesins bind microtubules - v56:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9783584] Update Tracker - [Reaction:983266] Kinesins bind microtubules - v56:[add_removeInput]
(precedingEvent)	[BlackBoxEvent:R-HSA-983259] Kinesins move along microtubules consuming ATP
(hasEvent)	[Pathway:R-HSA-983189] Kinesins

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