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Schema
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Entries
Nephron development
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authored
[InstanceEdit:9831925] May, Bruce, 2023-03-26
created
[InstanceEdit:9831927] May, Bruce, 2023-03-26
dbId
9831926
displayName
Nephron development
edited
[InstanceEdit:9831925] May, Bruce, 2023-03-26
eventOf
[Pathway:R-HSA-9830369] Kidney development - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:938377] metanephric nephron development
hasDiagram
true
hasEHLD
false
hasEvent
[Reaction:R-HSA-9833363] HNF1B binds the WNT9B gene - Homo sapiens
[BlackBoxEvent:R-HSA-9833362] Expression of WNT9B during nephron development - Homo sapiens
[BlackBoxEvent:R-HSA-9832331] Expression of WNT4 during nephron development - Homo sapiens
[BlackBoxEvent:R-HSA-9832340] Expression of LHX1 during nephron development - Homo sapiens
[BlackBoxEvent:R-HSA-9832230] Expression of POU3F3 during nephron development - Homo sapiens
[Reaction:R-HSA-9832083] HNF1B binds the DLL1 gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832209] Expression of DLL1 during nephron development - Homo sapiens
[Reaction:R-HSA-9832334] WT1 binds the PAX2 gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832187] Expression of JAG1 during nephron development - Homo sapiens
[Reaction:R-HSA-9832075] HNF1B binds the LFNG gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832205] Expression of LFNG during nephron development - Homo sapiens
[Reaction:R-HSA-9832665] HNF1B binds the HNF4A gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832687] Expression of HNF4A during nephron development - Homo sapiens
[Reaction:R-HSA-9832123] HNF1B binds the IRX1 gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832183] Expression of IRX1 during nephron development - Homo sapiens
[Reaction:R-HSA-9832112] HNF1B binds the IRX2 gene - Homo sapiens
[BlackBoxEvent:R-HSA-9832208] Expression of IRX2 during nephron development - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:9832383] Transcriptional control of terminal nephron differentiation
[LiteratureReference:9830472] Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies
[LiteratureReference:9832367] Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development
[LiteratureReference:9832344] Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development
[LiteratureReference:9832381] Disparate levels of beta-catenin activity determine nephron progenitor cell fate
[LiteratureReference:9792537] Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development
[LiteratureReference:9832370] Crucial roles of Brn1 in distal tubule formation and function in mouse kidney
[LiteratureReference:9832638] Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development
[LiteratureReference:9832654] Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis
maxDepth
2
modified
[InstanceEdit:9851767] May, Bruce, 2023-10-31
name
Nephron development
releaseDate
2023-12-06
reviewStatus
[ReviewStatus:9821383] three stars
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-9831926
summation
[Summation:9832342] A nephron of an amniote such as mouse or human comprises the...
Referrals
(hasEvent)
[Pathway:R-HSA-9830369] Kidney development
(hasEncapsulatedEvent)
[Pathway:R-HSA-3858494] Beta-catenin independent WNT signaling
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