Reactome | SERPINC1:HSPGs [plasma membrane]

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SERPINC1:HSPGs [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:9824036] serine-type endopeptidase inhibitor activity of SERPINC1:HSPGs [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9823281] FXa:SERPINC1:HS [plasma membrane] - Homo sapiens [Complex:R-HSA-140812] thrombin:SERPINC1:HSPGs [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9823284] FXa binds SERPINC1:HS - Homo sapiens [Reaction:R-HSA-140791] activated thrombin (factor IIa) + antithrombin III:heparan sulfate -> thrombin:antithrombin III:heparan sulfate - Homo sapiens
created	[InstanceEdit:9823294] Shamovsky, Veronica, 2023-01-05
dbId	9823297
displayName	SERPINC1:HSPGs [plasma membrane]
hasComponent	[DefinedSet:R-HSA-2076618] HSPGs [plasma membrane] [EntityWithAccessionedSequence:R-HSA-140807] SERPINC1 [extracellular region]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-9823297] SERPINC1:HSPGs [plasma membrane] - Mus musculus [Complex:R-RNO-9823297] SERPINC1:HSPGs [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9823297] SERPINC1:HSPGs [plasma membrane] - Canis familiaris [Complex:R-BTA-9823297] SERPINC1:HSPGs [plasma membrane] - Bos taurus [Complex:R-SSC-9823297] SERPINC1:HSPGs [plasma membrane] - Sus scrofa [Complex:R-DRE-9823297] SERPINC1:HSPGs [plasma membrane] - Danio rerio [Complex:R-XTR-9823297] SERPINC1:HSPGs [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-9823297] SERPINC1:HSPGs [plasma membrane] - Gallus gallus [Complex:R-DME-9823297] SERPINC1:HSPGs [plasma membrane] - Drosophila melanogaster
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9980381] Shamovsky, Veronica, 2026-01-28
name	SERPINC1:HSPGs ATIII:HS Antithrombin:heparan sulfate/heparin proteoglycans
producedByEvent	[Reaction:R-HSA-9823290] SERPINC1 binds heparan sulfate - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9823297

Referrals

(input)	[Reaction:R-HSA-9823284] FXa binds SERPINC1:HS [Reaction:R-HSA-140791] activated thrombin (factor IIa) + antithrombin III:heparan sulfate -> thrombin:antithrombin III:heparan sulfate
(physicalEntity)	[CatalystActivity:9824036] serine-type endopeptidase inhibitor activity of SERPINC1:HSPGs [plasma membrane]
(output)	[Reaction:R-HSA-9823290] SERPINC1 binds heparan sulfate
(hasComponent)	[Complex:R-HSA-140812] thrombin:SERPINC1:HSPGs [plasma membrane] [Complex:R-HSA-9823281] FXa:SERPINC1:HS [plasma membrane]

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