Reactome | Formation of axial mesoderm

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Formation of axial mesoderm Show undefined attributes

authored	[InstanceEdit:9796248] May, Bruce, 2022-08-06
created	[InstanceEdit:9796202] May, Bruce, 2022-08-09
dbId	9796292
displayName	Formation of axial mesoderm
doi	10.3180/R-HSA-9796292.1
edited	[InstanceEdit:9796248] May, Bruce, 2022-08-06
eventOf	[Pathway:R-HSA-9758941] Gastrulation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:160378] axial mesoderm formation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-9796225] TEAD2,TEAD4:YAP1, TBXT, FOXH1, and SMAD2,3 bind the FOXA2 gene - Homo sapiens [BlackBoxEvent:R-HSA-9796209] Expression of FOXA2 in the anterior primitive streak - Homo sapiens [BlackBoxEvent:R-HSA-9796300] Expression of NOTO in axial mesoderm - Homo sapiens [BlackBoxEvent:R-HSA-9815789] Expression of SHH in axial mesoderm - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9815845] Notochord morphogenesis in mice: Current understanding & open questions [LiteratureReference:9815918] Development of the axial skeleton and intervertebral disc [LiteratureReference:9796220] FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse [LiteratureReference:9796237] The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse [LiteratureReference:9794956] Charting Brachyury-mediated developmental pathways during early mouse embryogenesis [LiteratureReference:9818409] The prechordal plate, the rostral end of the notochord and nearby median features in staged human embryos [LiteratureReference:9818404] Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis [LiteratureReference:9796281] Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor
maxDepth	2
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of axial mesoderm
releaseDate	2022-12-07
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9818412] Sasaki, Hiroshi, 2022-10-15
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9796292
summation	[Summation:9815846] Axial mesoderm, also called chordamesoderm, is formed by cel...

Referrals

(hasEvent)

[Pathway:R-HSA-9758941] Gastrulation