Reactome | ST translocates from cytosol to mitochondrial matrix of hepatocytes

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9749700] Stephan, Ralf, 2021-08-04
category	uncertain
compartment	[Compartment:70101] cytosol [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9757453] Stephan, Ralf, 2021-11-01
dbId	9757454
displayName	ST translocates from cytosol to mitochondrial matrix of hepatocytes
edited	[InstanceEdit:9758462] Stephan, Ralf, 2021-11-12
eventOf	[Pathway:R-HSA-9749641] Aspirin ADME - Homo sapiens
followingEvent	[Pathway:R-HSA-177128] Conjugation of salicylate with glycine - Homo sapiens
input	[SimpleEntity:R-ALL-9749797] ST (hepatocyte) [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9750004] The metabolism of aspirin in man: a population study
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ST translocates from cytosol to mitochondrial matrix of hepatocytes Salicylate localizes to mitochondrial matrix
output	[SimpleEntity:R-ALL-159559] ST [mitochondrial matrix]
precedingEvent	[BlackBoxEvent:R-HSA-9757451] ASA-,ST translocate from cytosol to ER lumen of hepatocytes - Homo sapiens [Reaction:R-HSA-9749583] SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes - Homo sapiens
releaseDate	2021-12-08
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9756301] Huddart, Rachel, 2021-10-13
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9757454
summation	[Summation:9750700] It is not known how salicylate (ST) translocates to the mito...

(hasEvent)	[Pathway:R-HSA-9749641] Aspirin ADME
(precedingEvent)	[Pathway:R-HSA-177128] Conjugation of salicylate with glycine

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