Reactome | ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol]

Schema > Complex > Entries

ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-9758090] Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation - Homo sapiens
created	[InstanceEdit:9755502] Rothfels, Karen, 2021-10-08
dbId	9755501
displayName	ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol]
hasComponent	[Complex:R-HSA-9755498] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] [Complex:R-HSA-9755500] UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Mus musculus [Complex:R-RNO-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Rattus norvegicus [Complex:R-CFA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Canis familiaris [Complex:R-BTA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Bos taurus [Complex:R-SSC-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Sus scrofa [Complex:R-DRE-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Danio rerio [Complex:R-XTR-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Xenopus tropicalis [Complex:R-GGA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Gallus gallus [Complex:R-DME-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Drosophila melanogaster [Complex:R-CEL-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Caenorhabditis elegans [Complex:R-DDI-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Dictyostelium discoideum [Complex:R-SPO-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Schizosaccharomyces pombe [Complex:R-SCE-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Saccharomyces cerevisiae [Complex:R-PFA-9755501] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] - Plasmodium falciparum
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9758076] Rothfels, Karen, 2021-11-09
name	ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer
producedByEvent	[Reaction:R-HSA-9755507] UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9755501

Referrals

(output)	[Reaction:R-HSA-9755507] UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex
(input)	[Reaction:R-HSA-9758090] Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation

© 2026 Reactome

Cite Us!