Reactome | KRAB-ZNF / KAP Interaction

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KRAB-ZNF / KAP Interaction Show undefined attributes

authored	[InstanceEdit:975059] Caudy, M, 2010-09-22
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:975039] Caudy, M, 2010-09-22
dbId	975040
displayName	KRAB-ZNF / KAP Interaction
edited	[InstanceEdit:1080819] D'Eustachio, P, 2010-11-27
eventOf	[Pathway:R-HSA-212436] Generic Transcription Pathway - Homo sapiens
input	[DefinedSet:R-HSA-975006] KAP (KRAB-Domain Associated Protein) [nucleoplasm] [CandidateSet:R-HSA-974995] KRAB-ZNF [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:975057] A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors [LiteratureReference:975053] KAP-1, a novel corepressor for the highly conserved KRAB repression domain [LiteratureReference:1044510] KRAB-containing zinc-finger repressor proteins [LiteratureReference:1044517] Kr�ppel-associated boxes are potent transcriptional repression domains [LiteratureReference:1044503] KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kr�ppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	KRAB-ZNF / KAP Interaction
orthologousEvent	[Reaction:R-GGA-975040] KRAB-ZNF / KAP Interaction - Gallus gallus [Reaction:R-SSC-975040] KRAB-ZNF / KAP Interaction - Sus scrofa [Reaction:R-BTA-975040] KRAB-ZNF / KAP Interaction - Bos taurus [Reaction:R-RNO-975040] KRAB-ZNF / KAP Interaction - Rattus norvegicus [Reaction:R-MMU-975040] KRAB-ZNF / KAP Interaction - Mus musculus
output	[Complex:R-HSA-975037] KRAB-ZNF / KAP Complex [nucleoplasm]
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1217480] Rauscher, F, 2011-02-15
revised	[InstanceEdit:3343769] Caudy, M, 2013-05-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-975040
summation	[Summation:1027438] Formation of the KRAB ZNF / KAP1 Corepressor Complex:
updateTrackers	[UpdateTracker:9789658] Update Tracker - [Reaction:975040] KRAB-ZNF / KAP Interaction - v37:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9789658] Update Tracker - [Reaction:975040] KRAB-ZNF / KAP Interaction - v37:[modifyText]
(hasEvent)	[Pathway:R-HSA-212436] Generic Transcription Pathway