Reactome | TRPM5 transports Na+ from the extracellular region to the cytosol

Schema > Reaction > Entries

TRPM5 transports Na+ from the extracellular region to the cytosol Show undefined attributes

authored	[InstanceEdit:9717388] May, Bruce, 2021-03-10
catalystActivity	[CatalystActivity:9717373] sodium channel activity of TRPM5 tetramer [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9717391] May, Bruce, 2021-03-10
crossReference	[DatabaseIdentifier:12667893] RHEA:34963
dbId	9717395
displayName	TRPM5 transports Na+ from the extracellular region to the cytosol
edited	[InstanceEdit:9717388] May, Bruce, 2021-03-10
eventOf	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste - Homo sapiens
followingEvent	[Reaction:R-HSA-9717392] CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region - Homo sapiens
inferredFrom	[Reaction:R-MMU-9717433] Trpm5 transports Na+ from the extracellular region to the cytosol - Mus musculus
input	[SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:3296358] TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRPM5 transports Na+ from the extracellular region to the cytosol
output	[SimpleEntity:R-ALL-83910] Na+ [cytosol]
precedingEvent	[Reaction:R-HSA-9717215] ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol - Homo sapiens
regulatedBy	[PositiveRegulation:R-HSA-71542] Positive regulation by 'Ca2+ [cytosol]'
releaseDate	2021-09-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9749949] Jiang, Peihua, 2021-08-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9717395
summation	[Summation:9725647] TRPM5 is activated by calcium ions and passively transports ...

Referrals

(hasEvent)	[Pathway:R-HSA-9717207] Sensory perception of sweet, bitter, and umami (glutamate) taste
(precedingEvent)	[Reaction:R-HSA-9717392] CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region
(inferredTo)	[Reaction:R-MMU-9717433] Trpm5 transports Na+ from the extracellular region to the cytosol

Cite Us!