Reactome | p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9702485] Rothfels, Karen, 2020-09-30
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9702484
disease	[Disease:1500689] cancer
displayName	p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8983328] GRB2 [cytosol] [CandidateSet:R-HSA-9697968] p-6Y FLT3 ITD mutant dimers [plasma membrane] [EntityWithAccessionedSequence:R-HSA-912529] p-Y-GAB2 [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9702520] Rothfels, Karen, 2020-09-30
name	p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2
producedByEvent	[Reaction:R-HSA-9698013] PTPN11:p-STAT5 dissociates from mutant FLT3 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9702484
updateTrackers	[UpdateTracker:9905372] Update Tracker - [Complex:9702484] p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2 [plasma membrane] - v85:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9905372] Update Tracker - [Complex:9702484] p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2 [plasma membrane] - v85:[updateContainedComponent]
(output)	[Reaction:R-HSA-9698013] PTPN11:p-STAT5 dissociates from mutant FLT3

Cite Us!