Reactome | SARS-CoV-1 M protein interacts with TRAF3

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SARS-CoV-1 M protein interacts with TRAF3 Show undefined attributes

authored	[InstanceEdit:9692648] Shamovsky, Veronica, 2020-06-25
category	binding
compartment	[Compartment:20699] Golgi membrane [Compartment:70101] cytosol
created	[InstanceEdit:9685159] Shamovsky, Veronica, 2020-04-22
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9685162
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	SARS-CoV-1 M protein interacts with TRAF3
edited	[InstanceEdit:9796665] Shamovsky, Veronica, 2022-08-11
eventOf	[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-936402] K63polyUb-TRAF3 [cytosol] [EntityWithAccessionedSequence:R-COV-9683651] M [Golgi membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9685164] Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex [LiteratureReference:9685165] Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-1 M protein interacts with TRAF3
output	[Complex:R-HSA-9685166] M:K63polyUb-TRAF3 [Golgi membrane]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-09-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9713569] D'Eustachio, Peter, 2021-01-26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9685162
summation	[Summation:9685156] Severe acute respiratory syndrome coronavirus type 1 (SARS-C...

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[Pathway:R-HSA-9692916] SARS-CoV-1 activates/modulates innate immune responses

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