Reactome | E and N are recruited to the M lattice

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E and N are recruited to the M lattice Show undefined attributes

authored	[InstanceEdit:9685154] Rothfels, Karen, 2020-04-22
category	binding
compartment	[Compartment:6791047] endoplasmic reticulum-Golgi intermediate compartment membrane
created	[InstanceEdit:9684237] Rothfels, Karen, 2020-04-21
crossReference	[DatabaseIdentifier:12020764] Mondo:0005091
dbId	9684238
disease	[Disease:9678120] severe acute respiratory syndrome
displayName	E and N are recruited to the M lattice
edited	[InstanceEdit:9685483] Rothfels, Karen, 2020-04-23
eventOf	[Pathway:R-HSA-9679509] Virion Assembly and Release - Homo sapiens
followingEvent	[Reaction:R-HSA-9684241] Recruitment of Spike trimer to assembling virion - Homo sapiens
input	[Complex:R-COV-9684199] encapsidated SARS coronavirus genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane] [Complex:R-COV-9684216] M lattice [endoplasmic reticulum-Golgi intermediate compartment membrane] 3 × [Complex:R-COV-9683621] Ub-3xPalmC-E pentamer [Golgi membrane]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9680341] The molecular biology of coronaviruses [LiteratureReference:9679510] Human Coronavirus: Host-Pathogen Interaction [LiteratureReference:9685450] Incorporation of spike and membrane glycoproteins into coronavirus virions [LiteratureReference:9684168] Generation of synthetic severe acute respiratory syndrome coronavirus pseudoparticles: implications for assembly and vaccine production [LiteratureReference:9684137] Assembly of human severe acute respiratory syndrome coronavirus-like particles [LiteratureReference:9684142] Assembly of severe acute respiratory syndrome coronavirus RNA packaging signal into virus-like particles is nucleocapsid dependent [LiteratureReference:9684163] Efficient assembly and release of SARS coronavirus-like particles by a heterologous expression system [LiteratureReference:9684187] The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [LiteratureReference:9685370] The transmembrane oligomers of coronavirus protein E [LiteratureReference:9682946] Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein [LiteratureReference:9682982] Biochemical evidence for the presence of mixed membrane topologies of the severe acute respiratory syndrome coronavirus envelope protein expressed in mammalian cells [LiteratureReference:9685364] Interactions between M protein and other structural proteins of severe, acute respiratory syndrome-associated coronavirus [LiteratureReference:9685362] Expression and membrane integration of SARS-CoV E protein and its interaction with M protein [LiteratureReference:9685354] Coronavirus envelope protein: current knowledge [LiteratureReference:9685353] Coronavirus envelope protein: a small membrane protein with multiple functions [LiteratureReference:9684155] Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus [LiteratureReference:9685350] Characterization of protein-protein interactions between the nucleocapsid protein and membrane protein of the SARS coronavirus [LiteratureReference:9685368] Severe acute respiratory syndrome coronavirus membrane protein interacts with nucleocapsid protein mostly through their carboxyl termini by electrostatic attraction
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E and N are recruited to the M lattice
orthologousEvent	[Reaction:R-HSA-9694444] E and N are recruited to the M lattice - Homo sapiens
output	[Complex:R-COV-9684226] M lattice:E protein:encapsidated SARS coronavirus genomic RNA [endoplasmic reticulum-Golgi intermediate compartment membrane]
precedingEvent	[Reaction:R-HSA-9684218] M protein oligomerization - Homo sapiens [Reaction:R-HSA-9684234] Encapsidation of SARS coronavirus genomic RNA - Homo sapiens
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9684238
summation	[Summation:9685372] Formation of an M lattice nucleates recruitment of other str...
updateTrackers	[UpdateTracker:9776662] Update Tracker - [Reaction:9684238] E and N are recruited to the M lattice - v74:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9776662] Update Tracker - [Reaction:9684238] E and N are recruited to the M lattice - v74:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-9679509] Virion Assembly and Release
(precedingEvent)	[Reaction:R-HSA-9684241] Recruitment of Spike trimer to assembling virion

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