Reactome | CQ, HCQ diffuses from cytosol to endocytic vesicle lumen

Schema > Reaction > Entries

authored	[InstanceEdit:9699040] Gillespie, Marc E, 2020-09-09
category	transition
compartment	[Compartment:70101] cytosol [Compartment:528865] endocytic vesicle lumen
created	[InstanceEdit:9683486] Jassal, Bijay, 2020-04-16
dbId	9683478
displayName	CQ, HCQ diffuses from cytosol to endocytic vesicle lumen
edited	[InstanceEdit:9683486] Jassal, Bijay, 2020-04-16
eventOf	[Pathway:R-HSA-9678110] Attachment and Entry - Homo sapiens
followingEvent	[Reaction:R-HSA-9683467] CQ, HCQ are protonated to CQ2+, HCQ2+ - Homo sapiens
input	[DefinedSet:R-ALL-9685614] CQ, HCQ [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9685611] On the mechanism of chloroquine resistance in Plasmodium falciparum
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CQ, HCQ diffuses from cytosol to endocytic vesicle lumen
output	[DefinedSet:R-ALL-9685610] CQ, HCQ [endocytic vesicle lumen]
releaseDate	2020-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9683478
summation	[Summation:9684963] Unprotonated chloroquine (CQ) and hydroxychloroquine (HCQ) c...

(precedingEvent)	[Reaction:R-HSA-9683467] CQ, HCQ are protonated to CQ2+, HCQ2+
(hasEvent)	[Pathway:R-HSA-9678110] Attachment and Entry

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