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Schema
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Pathway
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Entries
Diseases of DNA Double-Strand Break Repair
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authored
[InstanceEdit:9707142] Orlic-Milacic, Marija, 2020-11-11
created
[InstanceEdit:9675138] Orlic-Milacic, Marija, 2020-01-31
crossReference
[DatabaseIdentifier:12020745] Mondo:0004992
dbId
9675136
disease
[Disease:1500689] cancer
displayName
Diseases of DNA Double-Strand Break Repair
edited
[InstanceEdit:9707276] Orlic-Milacic, Marija, 2020-11-12
eventOf
[Pathway:R-HSA-9675135] Diseases of DNA repair - Homo sapiens
figure
[Figure:9819168] /figures/ehld/R-HSA-9675136.svg
hasDiagram
true
hasEHLD
true
hasEvent
[Pathway:R-HSA-9663199] Defective DNA double strand break response due to BRCA1 loss of function - Homo sapiens
[Pathway:R-HSA-9699150] Defective DNA double strand break response due to BARD1 loss of function - Homo sapiens
[Pathway:R-HSA-9701192] Defective homologous recombination repair (HRR) due to BRCA1 loss of function - Homo sapiens
[Pathway:R-HSA-9701190] Defective homologous recombination repair (HRR) due to BRCA2 loss of function - Homo sapiens
[Pathway:R-HSA-9701193] Defective homologous recombination repair (HRR) due to PALB2 loss of function - Homo sapiens
isInDisease
true
isInferred
false
lastUpdatedDate
2022-12-07
literatureReference
[LiteratureReference:9707157] Monogenic Diseases of DNA Repair
[LiteratureReference:9707158] DNA double-strand break repair pathway choice - from basic biology to clinical exploitation
[LiteratureReference:9707154] DNA strand break repair and human genetic disease
maxDepth
4
modified
[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name
Diseases of DNA Double-Strand Break Repair
releaseDate
2020-12-08
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:9707277] D'Eustachio, Peter, 2020-11-11
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-9675136
summation
[Summation:9707163] Diseases of DNA double-strand break repair (DSBR) are caused...
updateTrackers
[UpdateTracker:9775776] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v78:[addHasEvent, updateContainedPathway]
[UpdateTracker:9846918] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v83:[modifyText]
[UpdateTracker:9776171] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v77:[addHasEvent]
[UpdateTracker:9775088] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v80:[addHasEvent]
Referrals
(updatedInstance)
[UpdateTracker:9775776] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v78:[addHasEvent, updateContainedPathway]
[UpdateTracker:9846918] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v83:[modifyText]
[UpdateTracker:9776171] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v77:[addHasEvent]
[UpdateTracker:9775088] Update Tracker - [Pathway:9675136] Diseases of DNA Double-Strand Break Repair - v80:[addHasEvent]
(hasEvent)
[Pathway:R-HSA-9675135] Diseases of DNA repair
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