Reactome | p-11Y kinase domain PDGFRA mutant dimers [plasma membrane]

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p-11Y kinase domain PDGFRA mutant dimers [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9672041] Rothfels, Karen, 2019-12-23
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9672056
disease	[Disease:1500689] cancer
displayName	p-11Y kinase domain PDGFRA mutant dimers [plasma membrane]
hasCandidate	[Complex:R-HSA-9674334] p-11Y PDGFRA D842L [plasma membrane] - Homo sapiens [Complex:R-HSA-9674337] p-11Y PDGFRA D846V dimer [plasma membrane] - Homo sapiens
hasMember	[Complex:R-HSA-9672048] p-10Y PDGFRA Y849C dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672044] p-11Y PDGFRA D842V dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672030] p-11Y PDGFRA D842Y dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672031] p-11Y PDGFRA D842_D846del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672063] p-11Y PDGFRA D842_H845del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672067] p-11Y PDGFRA D842_I843delinsV dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672070] p-11Y PDGFRA D842_M844del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672037] p-11Y PDGFRA D842del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672045] p-11Y PDGFRA D843_844del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672049] p-11Y PDGFRA D843_845 del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672060] p-11Y PDGFRA D843_846 del dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672042] p-11Y PDGFRA D846Y dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-9672051] p-11Y PDGFRA N848K dimer [plasma membrane] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:9671911] PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib
maxDepth	3
memberOf	[DefinedSet:R-HSA-9672040] p-11Y PDGFR mutant receptor dimers [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9674385] Rothfels, Karen, 2020-01-13
name	p-11Y kinase domain PDGFRA mutant dimers
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9672056

Referrals

(hasMember)

[DefinedSet:R-HSA-9672040] p-11Y PDGFR mutant receptor dimers [plasma membrane]

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