Reactome | ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[FailedReaction:R-HSA-9665708] ERBB2 TMD/JMD mutants do not bind pertuzumab - Homo sapiens
created	[InstanceEdit:9665965] Orlic-Milacic, Marija, 2019-11-01
dbId	9665969
displayName	ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]
hasComponent	[Complex:R-HSA-1225828] CDC37 [cytosol] [DefinedSet:R-HSA-9665964] ERBB2 TMD/JMD mutants (pertuzumab resistant) [plasma membrane] [EntityWithAccessionedSequence:R-HSA-1358718] ERBIN [plasma membrane] [Complex:R-HSA-1221657] HSP90 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	3
name	ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9665969

(input)	[FailedReaction:R-HSA-9665708] ERBB2 TMD/JMD mutants do not bind pertuzumab
(diseaseEntity)	[EntityFunctionalStatus:9665966] loss_of_function of ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]

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