Reactome | NF1 GTPase mutants:SPRED dimer:p21 RAS:GTP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[FailedReaction:R-HSA-6802837] Loss-of-function NF1 variants don't stimulate RAS GTPase activity - Homo sapiens
created	[InstanceEdit:9665333] Rothfels, Karen, 2019-10-30
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9665332
disease	[Disease:1500689] cancer
displayName	NF1 GTPase mutants:SPRED dimer:p21 RAS:GTP [plasma membrane]
hasComponent	[CandidateSet:R-HSA-6802562] NF1 GTPase mutants [cytosol] [Complex:R-HSA-109783] p21 RAS:GTP [plasma membrane] [CandidateSet:R-HSA-5658219] SPRED dimer [plasma membrane]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	4
name	NF1 GTPase mutants:SPRED dimer:p21 RAS:GTP
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9665332

(input)	[FailedReaction:R-HSA-6802837] Loss-of-function NF1 variants don't stimulate RAS GTPase activity
(diseaseEntity)	[EntityFunctionalStatus:6802838] loss_of_function of NF1 GTPase mutants:SPRED dimer:p21 RAS:GTP [plasma membrane]

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