Reactome | RB1 mutants (E2F binding) [nucleoplasm]

Schema > CandidateSet > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[FailedReaction:R-HSA-9659782] Defective RB1 does not bind E2F1,(E2F2,E2F3) - Homo sapiens
created	[InstanceEdit:9659788] Orlic-Milacic, Marija, 2019-09-05
dbId	9659785
displayName	RB1 mutants (E2F binding) [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-9659807] RB1 R661Q [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9659821] RB1 C706Y [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9661065] RB1 I703_E737del [nucleoplasm] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-9659792] RB1 N480del [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9659801] RB1 R661W [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9659812] RB1 C706F [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-9661042] RB1 T738_R775del [nucleoplasm] - Homo sapiens
inDisease	false
maxDepth	2
modified	[InstanceEdit:9687153] Orlic-Milacic, Marija, 2020-05-06
name	RB1 mutants (E2F binding)
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-9659785

(input)	[FailedReaction:R-HSA-9659782] Defective RB1 does not bind E2F1,(E2F2,E2F3)
(diseaseEntity)	[EntityFunctionalStatus:9659798] loss_of_function and partial_loss_of_function of RB1 mutants (E2F binding) [nucleoplasm]