Reactome | activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane]

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activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9657593] Rothfels, Karen, 2019-08-08
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	9657592
disease	[Disease:1500689] cancer
displayName	activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane]
hasComponent	[Complex:R-HSA-5672724] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] [CandidateSet:R-ALL-9657577] single mechanism MAPK inhibitors [cytosol]
inDisease	true
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Mus musculus [Complex:R-RNO-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Canis familiaris [Complex:R-BTA-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Bos taurus [Complex:R-SSC-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Sus scrofa [Complex:R-DRE-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Danio rerio [Complex:R-GGA-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Gallus gallus [Complex:R-DME-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Caenorhabditis elegans [Complex:R-DDI-9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - Dictyostelium discoideum
isChimeric	false
maxDepth	12
name	activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors
producedByEvent	[Reaction:R-HSA-9657608] Single mechanism MAPK inhibitors bind phosphorylated MAPK - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9657592
updateTrackers	[UpdateTracker:9905402] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v85:[updateContainedComponent] [UpdateTracker:9928670] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v91:[updateContainedComponent] [UpdateTracker:9919553] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v90:[updateContainedComponent]

Referrals

(updatedInstance)

[UpdateTracker:9905402] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v85:[updateContainedComponent]
[UpdateTracker:9928670] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v91:[updateContainedComponent]
[UpdateTracker:9919553] Update Tracker - [Complex:9657592] activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] - v90:[updateContainedComponent]

(output)

[Reaction:R-HSA-9657608] Single mechanism MAPK inhibitors bind phosphorylated MAPK

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