Reactome | 2xPDXK:2xZn2+ phosphorylates PXA

Schema > Reaction > Entries

2xPDXK:2xZn2+ phosphorylates PXA Show undefined attributes

authored	[InstanceEdit:964978] Stephan, R, 2010-09-16
catalystActivity	[CatalystActivity:965111] pyridoxal kinase activity of 2xPDXK:2xZn2+ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:965238] Jassal, B, 2010-09-20
crossReference	[DatabaseIdentifier:12668279] RHEA:25105
dbId	964958
displayName	2xPDXK:2xZn2+ phosphorylates PXA
edited	[InstanceEdit:965238] Jassal, B, 2010-09-20
eventOf	[Pathway:R-HSA-964975] Vitamin B6 activation to pyridoxal phosphate - Homo sapiens
followingEvent	[Reaction:R-HSA-965079] 2xPNPO:2xFMN oxidizes PXAP to PXLP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-964945] PXA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:964963] Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases [LiteratureReference:965121] Human pyridoxal kinase: overexpression and properties of the recombinant enzyme
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	2xPDXK:2xZn2+ phosphorylates PXA Pyridoxamine is phosphorylated
orthologousEvent	[Reaction:R-PFA-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Plasmodium falciparum [Reaction:R-SCE-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Saccharomyces cerevisiae [Reaction:R-SPO-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Schizosaccharomyces pombe [Reaction:R-DDI-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Dictyostelium discoideum [Reaction:R-CEL-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Caenorhabditis elegans [Reaction:R-DME-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Drosophila melanogaster [Reaction:R-GGA-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Gallus gallus [Reaction:R-XTR-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Xenopus tropicalis [Reaction:R-DRE-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Danio rerio [Reaction:R-SSC-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Sus scrofa [Reaction:R-BTA-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Bos taurus [Reaction:R-CFA-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Canis familiaris [Reaction:R-RNO-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Rattus norvegicus [Reaction:R-MMU-964958] 2xPDXK:2xZn2+ phosphorylates PXA - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-965146] PXAP [cytosol]
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:997376] D'Eustachio, P, 2010-11-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-964958
summation	[Summation:996706] Pyridoxal kinase (PDXK) catalyzes the ATP-dependent phosphor...
updateTrackers	[UpdateTracker:9788027] Update Tracker - [Reaction:964958] 2xPDXK:2xZn2+ phosphorylates PXA - v44:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9788027] Update Tracker - [Reaction:964958] 2xPDXK:2xZn2+ phosphorylates PXA - v44:[modifyText]
(precedingEvent)	[Reaction:R-HSA-965079] 2xPNPO:2xFMN oxidizes PXAP to PXLP
(hasEvent)	[Pathway:R-HSA-964975] Vitamin B6 activation to pyridoxal phosphate