Reactome | PPM1E dephosphorylates CAMK4

Schema > Reaction > Entries

authored	[InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
catalystActivity	[CatalystActivity:9619429] protein serine/threonine phosphatase activity of PPM1E [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9619431] Orlic-Milacic, Marija, 2018-09-17
dbId	9619430
displayName	PPM1E dephosphorylates CAMK4
edited	[InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
eventOf	[Pathway:R-HSA-9617324] Negative regulation of NMDA receptor-mediated neuronal transmission - Homo sapiens
inferredFrom	[Reaction:R-RNO-9619441] Ppm1e dephosphorylates Camk4 - Rattus norvegicus
input	[SimpleEntity:R-ALL-113518] H2O [nucleoplasm] [Complex:R-HSA-9619152] p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:9619426] Subcellular distributions of rat CaM kinase phosphatase N and other members of the CaM kinase regulatory system
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PPM1E dephosphorylates CAMK4
output	[Complex:R-HSA-112281] CAMK4:CALM1:4xCa2+ [nucleoplasm] [SimpleEntity:R-ALL-113550] Pi [nucleoplasm]
releaseDate	2018-12-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9619430
summation	[Summation:9619436] Nuclear protein phosphatase 1E (PPM1E, also known as CaM kin...

(hasEvent)	[Pathway:R-HSA-9617324] Negative regulation of NMDA receptor-mediated neuronal transmission
(inferredTo)	[Reaction:R-RNO-9619441] Ppm1e dephosphorylates Camk4

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