Reactome | ESCRT Disassembly

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ESCRT Disassembly Show undefined attributes

authored	[InstanceEdit:933345] Gillespie, ME, 2010-08-10
catalystActivity	[CatalystActivity:917728] ATP hydrolysis activity of Vps/Vta1 [cytosol]
category	transition
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:917715] Gillespie, ME, 2010-07-29
dbId	917693
displayName	ESCRT Disassembly
edited	[InstanceEdit:933345] Gillespie, ME, 2010-08-10
eventOf	[Pathway:R-HSA-917729] Endosomal Sorting Complex Required For Transport (ESCRT) - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-917699] ESCRT-III/Cargo Complex [endosome membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:933367] ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles [LiteratureReference:933353] Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	ESCRT Disassembly
orthologousEvent	[Reaction:R-DDI-917693] ESCRT Disassembly - Dictyostelium discoideum [Reaction:R-GGA-917693] ESCRT Disassembly - Gallus gallus [Reaction:R-DRE-917693] ESCRT Disassembly - Danio rerio [Reaction:R-SSC-917693] ESCRT Disassembly - Sus scrofa [Reaction:R-BTA-917693] ESCRT Disassembly - Bos taurus [Reaction:R-RNO-917693] ESCRT Disassembly - Rattus norvegicus [Reaction:R-MMU-917693] ESCRT Disassembly - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-HSA-917705] CHMP2 [cytosol] [EntityWithAccessionedSequence:R-HSA-917722] CHMP3 [cytosol] [DefinedSet:R-HSA-917714] CHMP4 [cytosol] [EntityWithAccessionedSequence:R-HSA-917736] CHMP6 [cytosol] [EntityWithAccessionedSequence:R-HSA-917703] CHMP7 [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-HSA-917712] Ubiquinated and PIP3 Endosmal Membrane Bound Cargo [endocytic vesicle membrane]
precedingEvent	[Reaction:R-HSA-917700] MVB Vesicle Formation - Homo sapiens
releaseDate	2011-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165091] Rush, MG, 2008-01-11 00:00:00
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-917693
summation	[Summation:933385] Disassembly Phase The AAA-ATPase, Vps4 disassembles ESC...

Referrals

(hasEvent)

[Pathway:R-HSA-917729] Endosomal Sorting Complex Required For Transport (ESCRT)