Reactome | Formation of meiotic heteroduplex

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Formation of meiotic heteroduplex Show undefined attributes

authored	[InstanceEdit:913923] May, B, 2010-07-19
catalystActivity	[CatalystActivity:913192] DNA strand exchange activity of Meiotic single-stranded DNA complex [nucleoplasm]
catalystActivityReference	[CatalystActivityReference:9643561] recombinase activity of Meiotic single-stranded DNA complex [nucleoplasm] Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:912491] May, B, 2010-07-08
dbId	912458
displayName	Formation of meiotic heteroduplex
edited	[InstanceEdit:913923] May, B, 2010-07-19
eventOf	[Pathway:R-HSA-912446] Meiotic recombination - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-912496] Formation of meiotic holliday junction - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-912431] Formation of Meiotic Heteroduplex - Mus musculus
input	[OtherEntity:R-ALL-29428] DNA [nucleoplasm] [Complex:R-HSA-912507] Meiotic single-stranded DNA complex [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:913210] Temporal progression of recombination in human males [LiteratureReference:913216] Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro [LiteratureReference:913234] Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange [LiteratureReference:913262] Distribution of the Rad51 recombinase in human and mouse spermatocytes [LiteratureReference:913303] Synergistic actions of Rad51 and Rad52 in recombination and DNA repair [LiteratureReference:83614] Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. [LiteratureReference:913215] Formation and branch migration of Holliday junctions mediated by eukaryotic recombinases [LiteratureReference:913251] The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51 [LiteratureReference:913318] Analysis of replication protein A (RPA) in human spermatogenesis
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of meiotic heteroduplex Meiotic Strand Invasion
output	[Complex:R-HSA-912484] Meiotic D-loop complex [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-912503] Formation of meiotic single-stranded DNA invasion complex - Homo sapiens
regulatedBy	[PositiveRegulation:R-HSA-913507] Positive regulation by 'HOP2(TBPIP):MND1 [nucleoplasm]'
regulationReference	[RegulationReference:9642310] Positive regulation by 'HOP2(TBPIP):MND1 [nucleoplasm]' Stimulation of DNA strand exchange by the human TBPIP/Hop2-Mnd1 complex
releaseDate	2011-03-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1221628] Bolcun-Filas, E, 2011-02-25 [InstanceEdit:1181360] Cohen, PE, 2011-02-04 [InstanceEdit:1181371] Holloway, JK, 2011-02-04 [InstanceEdit:1221625] Lyndaker, A, 2011-02-25 [InstanceEdit:1181380] Schimenti, JC, 2011-02-04 [InstanceEdit:1221623] Strong, E, 2011-02-25
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-912458
summation	[Summation:914141] Following double strand break (DSB) formation and strand res... [Summation:913506] The HOP2(TBPIP):MND1 complex stimulates RAD51 and DMC1 media...

Referrals

(hasEvent)	[Pathway:R-HSA-912446] Meiotic recombination
(precedingEvent)	[BlackBoxEvent:R-HSA-912496] Formation of meiotic holliday junction
(inferredTo)	[BlackBoxEvent:R-MMU-912431] Formation of Meiotic Heteroduplex

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