Reactome | Biosynthesis of DPAn-3-derived maresins

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Biosynthesis of DPAn-3-derived maresins Show undefined attributes

authored	[InstanceEdit:9026287] Jassal, Bijay, 2017-10-19
created	[InstanceEdit:9026287] Jassal, Bijay, 2017-10-19
crossReference	[DatabaseIdentifier:12819487] BioModels Database:BIOMD0000000106
dbId	9026290
displayName	Biosynthesis of DPAn-3-derived maresins
edited	[InstanceEdit:9026287] Jassal, Bijay, 2017-10-19
eventOf	[Pathway:R-HSA-9025094] Biosynthesis of DPAn-3 SPMs - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:9980] lipoxygenase pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-9026006] ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 - Homo sapiens [Reaction:R-HSA-9026007] ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 - Homo sapiens [Reaction:R-HSA-9026005] ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA - Homo sapiens [Reaction:R-HSA-9025998] Epoxide hydrolase hydrolyses 13,14-epoxy-DPAn-3 to MaR1n-3 DPA or MaR2n-3 DPA - Homo sapiens [BlackBoxEvent:R-HSA-9031894] DPAn-3 maresins translocate from cytosol to extracellular region - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-06-13
literatureReference	[LiteratureReference:9025105] Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid [LiteratureReference:9025095] Novel n-3 immunoresolvents: structures and actions
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Biosynthesis of DPAn-3-derived maresins
orthologousEvent	[Pathway:R-DDI-9026290] Biosynthesis of DPAn-3-derived maresins - Dictyostelium discoideum [Pathway:R-GGA-9026290] Biosynthesis of DPAn-3-derived maresins - Gallus gallus [Pathway:R-XTR-9026290] Biosynthesis of DPAn-3-derived maresins - Xenopus tropicalis [Pathway:R-DRE-9026290] Biosynthesis of DPAn-3-derived maresins - Danio rerio [Pathway:R-SSC-9026290] Biosynthesis of DPAn-3-derived maresins - Sus scrofa [Pathway:R-BTA-9026290] Biosynthesis of DPAn-3-derived maresins - Bos taurus [Pathway:R-CFA-9026290] Biosynthesis of DPAn-3-derived maresins - Canis familiaris [Pathway:R-RNO-9026290] Biosynthesis of DPAn-3-derived maresins - Rattus norvegicus [Pathway:R-MMU-9026290] Biosynthesis of DPAn-3-derived maresins - Mus musculus
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-9026290
summation	[Summation:9026294] The polyunsaturated fatty acid (PUFA) ?-3 cis-7,10,13,16,19-...
updateTrackers	[UpdateTracker:9779405] Update Tracker - [Pathway:9026290] Biosynthesis of DPAn-3-derived maresins - v65:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9779405] Update Tracker - [Pathway:9026290] Biosynthesis of DPAn-3-derived maresins - v65:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-9025094] Biosynthesis of DPAn-3 SPMs