Reactome | MECP2 binds SGK1 gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:9024208] Orlic-Milacic, Marija, 2017-10-02
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9022769] Orlic-Milacic, Marija, 2017-09-25
dbId	9022770
displayName	MECP2 binds SGK1 gene promoter
edited	[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
eventOf	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2 - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9022764] SGK1 gene expression is inhibited by MECP2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-9022767] Mecp2 binds Sgk1 gene promoter - Mus musculus
input	[CandidateSet:R-HSA-9005549] MECP2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9022779] SGK1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MECP2 binds SGK1 gene promoter
output	[Complex:R-HSA-9022789] MECP2:SGK1 gene [nucleoplasm]
releaseDate	2018-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07 [InstanceEdit:9608114] Christodoulou, John, 2018-08-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9022770
summation	[Summation:9022768] Based on studies in mice, MECP2 binds the promoter of the SG...

(hasEvent)	[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
(precedingEvent)	[BlackBoxEvent:R-HSA-9022764] SGK1 gene expression is inhibited by MECP2
(inferredTo)	[Reaction:R-MMU-9022767] Mecp2 binds Sgk1 gene promoter

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