Reactome | DLX5,(DLX6):RUNX2 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9007720] Orlic-Milacic, Marija, 2017-06-02
dbId	9007721
displayName	DLX5,(DLX6):RUNX2 gene [nucleoplasm]
hasComponent	[CandidateSet:R-HSA-9007779] DLX5,(DLX6) [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8939903] RUNX2 gene [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:9007714] Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter [LiteratureReference:9007782] The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
maxDepth	3
modified	[InstanceEdit:9007784] Orlic-Milacic, Marija, 2017-06-05
name	DLX5,(DLX6):RUNX2 gene
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-9007725] Positive gene expression regulation by 'DLX5,(DLX6):RUNX2 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-9007707] DLX5,(DLX6) binds RUNX2 gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9007721

(output)	[Reaction:R-HSA-9007707] DLX5,(DLX6) binds RUNX2 gene promoter
(regulator)	[PositiveGeneExpressionRegulation:R-HSA-9007725] Positive gene expression regulation by 'DLX5,(DLX6):RUNX2 gene [nucleoplasm]'

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